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An experimental GLP-1 pill helped people with obesity or overweight lose as much as 12.1% of their body weight in just 36 weeks. Unlike injectable drugs such as Wegovy and Ozempic, aleniglipron is a small molecule that can be taken once daily with or without food and could potentially be produced more easily at scale.

Silver nanocatalysts have been found to switch where they perform their most important reactions depending on whether a solid oxide cell is making electricity or hydrogen. The discovery could enable smarter catalyst designs that boost clean power generation while making green hydrogen more energy-efficient.

A total solar eclipse will plunge parts of Europe into darkness on August 12, 2026, with Spain offering some of the best views. ESA will livestream the spectacle from the Javalambre Observatory, combining telescope feeds, drone footage, and expert commentary. At 20:31 CEST, the observatory will experience 1 minute and 21 seconds of totality, revealing the Sun’s normally hidden outer atmosphere.

NASA engineers have found a clever way to squeeze more life out of Voyager 2, nearly half a century after it left Earth. In an operation nicknamed the “Big Bang,” the team simultaneously shut down certain power-hungry hardware and switched to lower-power alternatives while keeping the spacecraft warm enough to survive.

Dogs have been shaping—and being shaped by—humans for about 15,000 years, evolving from early partners of hunter-gatherers into an astonishing range of specialized companions. Across the globe, they adapted alongside people to wildly different environments and needs, from powerful Arctic sled dogs and agile rainforest hunters to high-altitude dogs with genetic traits for surviving thin air. Some were even bred for wool, while others played important spiritual or ceremonial roles.

More than 60,000 years ago, humans in southern Africa were engraving ostrich eggshells with intricate geometric patterns that appear far more organized than previously realized. Researchers found recurring grids, parallel lines, right angles, and repeated shapes, suggesting the designs followed deliberate rules rather than being improvised. The engravers may even have planned entire patterns in their minds before carving them.

Very high levels of the inherited cholesterol-related particle Lp(a) were linked to a greater risk of major cardiovascular events, particularly stroke and cardiovascular death, in a study of more than 20,000 people. Since elevated Lp(a) often flies completely under the radar, a simple blood test could uncover hidden heart risk that standard cholesterol testing may miss.

A study tracking more than 340,000 adults for over a decade found that heavy drinking increased the risk of death regardless of beverage type. At lower levels, however, the picture became more surprising: beer, cider, and spirits were linked to higher mortality, while wine was associated with lower risk. Moderate wine drinkers had a 21% lower risk of cardiovascular death compared with people who rarely or never drank.

The rise of the potato in the Andes appears to have left a lasting mark on human DNA. Indigenous Peruvians carry exceptionally high numbers of a starch-digestion gene, likely because people with more copies gained an evolutionary advantage once potatoes became a staple food. The change began thousands of years before European contact, providing unusually strong evidence that diet can shape human evolution.

A daily glass of 100% fruit juice or a smoothie may help improve more than just fruit intake. In a small four-week trial, participants who added one to a healthier diet showed significantly lower depression scores, hinting that a simple dietary change could also support mental well-being.

Just a couple of hours of strength training each week could have surprisingly powerful effects on longevity. People who lifted weights for around 90 to 120 minutes weekly had a 13% lower risk of dying early, with especially large reductions in deaths from cardiovascular and neurological diseases. Pairing strength training with regular aerobic exercise was even more impressive, lowering overall death risk by about 45%.

A 240-million-year-old reptile discovered in Brazil is revealing what evolution looked like just before the rise of dinosaurs and crocodiles. The small predator had unusually positioned legs that may have allowed it to move more efficiently than many earlier reptiles. Its close relatives were previously known mostly from other continents, suggesting these ancient animals spread much farther across the Triassic world than scientists realized.

Frequent cannabis users may wake up with unusually high levels of the stress hormone cortisol, suggesting their daily stress rhythms could be disrupted. Researchers say the finding raises questions about whether using cannabis for stress relief might, over time, interfere with the very system that helps the body handle stress.

Full-fat dairy may be healthier than conventional advice has suggested. In a 12-week study, adults who ate three servings a day showed no meaningful increases in weight, body fat, cholesterol, or insulin resistance. They also experienced improved blood pressure and consumed more calcium, protein, and vitamin D. The findings suggest dairy’s complex structure may matter more than its saturated fat content alone.

Atomically thin semiconductors could enable dramatically smaller and more efficient chips, but a stubborn problem at the boundary between materials has limited their performance. Researchers have now engineered that atomic interface to protect electron flow while still allowing extremely thin insulating layers. The resulting transistors delivered an unusually strong combination of electrical control and performance.

An intensive seven-day meditation retreat triggered striking changes across the brain and body, including shifts tied to neuroplasticity, immunity, metabolism, and natural pain relief. Participants also showed brain connectivity patterns resembling those associated with psychedelic experiences, suggesting that powerful altered states may be achievable without drugs.

Changing how much sweet-tasting food people eat may not change how much they crave or enjoy sweetness after all. In a six-month trial, researchers found that people assigned to high-, low-, or average-sweetness diets showed no meaningful differences in their preference for sweet foods, body weight, or markers linked to diabetes and heart disease. Many participants also drifted back toward their previous eating habits once the trial ended.

Cassini data has revealed a surprising twist in Saturn’s magnetic shield: the planet’s rapid rotation appears to drag a key opening in its magnetosphere far toward the afternoon side instead of keeping it near noon, as happens on Earth. The finding confirms that giant planets like Saturn operate under a fundamentally different magnetic regime, where fast spin and charged material from moons such as Enceladus can overpower the Sun’s influence.

Stress may literally scramble the brain’s internal GPS. Researchers found that cortisol, a hormone released during stress, made people significantly worse at navigating a virtual environment and disrupted the precise activity of grid cells, specialized brain cells that help us understand where we are in space. When landmarks were missing, this navigation system nearly stopped functioning, while another brain region appeared to step in and compensate.

Deep underground, bacteria may be capable of doing something remarkable: trapping toxic uranium before it spreads. When researchers fed microbes in uranium-contaminated mine water with glycerol, about 95% of the dissolved uranium disappeared within 130 days. The bacteria helped convert it into an unusually stable uranium compound that had rarely been observed before.

Chemists have developed a catalyst that breaks a long-standing rule governing which molecules receive electrons during chemical reactions. By releasing electrons directly into solution, the technique could unlock reactions—and potentially useful new molecules—that were previously out of reach.

A rare meteorite that crashed through a New Jersey roof contains evidence of ancient salty fluids, organic compounds, and amino acids from a primitive asteroid. Its pristine chemistry could offer new clues about how space rocks helped supply early Earth with some of the ingredients needed for life.

CT scans of the world’s rarest dodo skulls suggest the extinct bird may have had a stronger sense of smell, a highly sensitive beak, and a lifestyle that extended into dawn and dusk. The discoveries are helping overturn centuries-old myths and reveal a far more complex animal than the famously “dumb” dodo of popular imagination.

Scientists have discovered incredibly tiny plasma whirlpools swirling across the Sun’s surface, some just 20 kilometers wide. These previously invisible vortices may twist magnetic fields and help build up the energy released in small solar eruptions called nanoflares. They may also help magnetic fields spread through the Sun’s atmosphere far faster than current models can explain.

A new nanostructured carbon design lets fuel-cell catalysts use tiny amounts of platinum while remaining remarkably stable and efficient. The breakthrough could help hydrogen fuel cells become a more practical way to power data centers, vehicles, and other energy-intensive technologies.

Dinosaurs conquered the land at enormous sizes, but strangely, they almost never evolved into truly tiny animals. New research suggests that physiology alone can’t explain this missing miniature end of the dinosaur spectrum—and that early mammals may have been partly responsible. While dinosaurs kept mammals from becoming large, small mammals may have returned the favor by occupying ecological niches that could otherwise have supported mouse-sized dinosaurs.

Scientists have generated quantum entanglement directly from sunlight, potentially offering a lower-energy alternative to the lasers normally used in quantum technology. Their outdoor experiment produced entangled photons with about 94% similarity to an ideal state. The result could pave the way for simpler quantum satellites, secure communications, and more energy-efficient quantum computing.

Genetic changes may set off a chain reaction that causes the spine’s natural shock absorbers to harden and deteriorate. Zebrafish with a faulty collagen-related gene developed mineral buildup and spinal fusion similar to human disc disease. Researchers were able to reduce the damage using an existing osteoporosis drug and by targeting fat metabolism. The discovery points to several exciting possibilities for future back pain treatments.

Teens who start using cannabis may experience slower growth in memory, attention, language, and processing speed. Their abilities often developed normally at first, then began leveling off while nonusers continued improving. THC appeared to be the most likely driver, especially for worsening memory.

Getting the recommended 150 minutes of moderate-to-vigorous exercise each week may offer only modest protection against heart attacks and strokes. A large study suggests that substantially greater benefits may require roughly 560 to 610 minutes a week—nearly 9 to 10 hours of brisk walking, running, cycling, or similar activity.

A ten-month Antarctic experiment found that astronauts may struggle not only with loneliness but also with spending too much time around the same people. Frequent contact was linked to greater tension and mistrust, while the crew increasingly divided into cultural and language-based groups.

More than 5,000 years after his death, Ötzi the Iceman is still hosting a remarkable mix of ancient and modern microorganisms. Researchers separated microbes that lived in his body during his lifetime from those that arrived after his death, uncovering traces of his original gut bacteria and cold-loving yeasts that may have survived alongside him in the glacier for millennia.

Linus Pauling was widely mocked for claiming that vitamin C could fight cancer, especially after trials using vitamin C pills showed no benefit. Researchers now know that intravenous vitamin C reaches vastly higher concentrations and can behave more like an experimental cancer drug than an ordinary supplement. Early studies suggest it may damage vulnerable cancer cells, reduce treatment side effects, and possibly improve outcomes for some patients.

Earth’s molten iron core unexpectedly reversed direction beneath the Pacific, revealing a dramatic change in the hidden engine that creates our planet’s magnetic field. Satellite data suggest the surge is already weakening, raising the possibility that the deep-Earth upheaval is part of a mysterious natural cycle.

A new wearable patch may help people reach REM sleep faster and remain there longer without medication or surgery. In a study of 28 participants, the device shortened the time to REM by 43 minutes and extended it by about 16 minutes. Researchers also observed signs of improved stress regulation and changes in brain circuits tied to emotion.

Scientists have created the first quantum material that can sort and transport different quantum states of light at room temperature, potentially removing the need for bulky, ultra-cold refrigeration systems. Built from a gold film carved with hundreds of microscopic structures, the ultrathin “metacrystal” acts like a filter that directs different kinds of quantum light along separate paths while preserving the information they carry.

A protein that evolved long before the human circulatory system may help unlock stronger cancer treatments. When C3 is produced inside tumors, it blocks immune-suppressing cells and gives immunotherapy a better chance to work. Researchers were even able to recreate this effect in resistant tumors, significantly improving survival in mice.

Beginning around age 50, the brain’s memory center appears to lose many of its longtime immune cells and replace them with more inflammatory ones. This surprising shift may help explain how normal aging sets the stage for Alzheimer’s disease and dementia.

A landmark study of nearly 4,000 babies found that acetaminophen and ibuprofen were equally safe during infancy. Neither medicine was linked to eczema or bronchiolitis, and no serious side effects were caused by the drugs. Researchers will continue following the children through age six to study possible long-term effects.

Blocking the glycine transporter SLC6A20 restored important brain signaling and improved social, communication, and repetitive behaviors in autism-related mouse models. The treatment also worked in human brain organoids and showed lasting effects in adult mice, suggesting the brain may remain more treatable later in life than previously thought.

Scientists have demonstrated that heat can move through a crystal in focused, wave-like rays at room temperature instead of spreading randomly. The breakthrough could make it possible to route heat around sensitive parts of next-generation chips and quantum devices.

Metal-rich asteroids could one day become hardware stores for Mars, supplying the materials needed to build and repair a growing colony. A new analysis shows that carefully selected asteroids may be reachable with current spacecraft technology. Some could even provide the ingredients for making rocket fuel in space, dramatically reducing the burden of hauling supplies from Earth.

Several enormous Megalodon vertebrae thought to have been destroyed in 1989 were found sitting unnoticed on a museum shelf. Their analysis strengthens evidence that the giant shark could exceed 24 meters (79 feet) in length and live for nearly a century. Researchers also estimate that its newborns may have measured an astonishing 3.6 meters (12 feet).

A supermassive black hole has been found lurking about 30,000 light-years from the center of its galaxy—the first dormant black hole detected so far from a galactic core. It revealed itself only after shredding a passing star and producing a brief, brilliant flare. Astronomers think it may be the remnant of a devoured galaxy or a black hole flung outward during a chaotic cosmic encounter.

Millions of sperm do not always compete alone—some species send them into action as coordinated teams. A sweeping evolutionary study found that this cooperation is widespread among arthropods and has repeatedly emerged and vanished over hundreds of millions of years. The discovery challenges the classic “fastest sperm wins” story and could influence future fertility research and pest-control strategies.

Ancient seafloor sediments have revealed a surprising twist in how the Atlantic’s massive circulation system works. During a cold period about 3.4 million years ago, the flow of warm, salty water from the Indian Ocean into the Atlantic nearly shut down—but the AMOC did not weaken as expected. Parts of the overturning circulation actually grew stronger.

Tiny pollution particles from smoke, soot, and dust may worsen rheumatoid arthritis and raise the risk of painful flares, particularly after prolonged exposure. The findings suggest that avoiding poor air quality could become an important part of managing the disease.

A prescription form of THC helped many people with PTSD escape recurring trauma-related nightmares, with more than one-third reporting that the nightmares disappeared completely after ten weeks. The results could point toward a long-awaited treatment for one of PTSD’s most distressing and stubborn symptoms.

A massive magma reservoir has been detected deep beneath Tuscany, despite showing no obvious signs at the surface. Scientists mapped the roughly 6,000-cubic-kilometer body using natural ground vibrations recorded by dozens of seismic sensors. It poses no immediate danger, but the discovery reveals how enormous volcanic systems can remain hidden and could transform the search for geothermal energy and critical minerals.

A spectacular fossil site in Canada contains 567-million-year-old creatures that may represent some of the earliest animals to move, reproduce sexually, and develop recognizable body plans. The discovery pushes key evolutionary milestones back by up to 10 million years and suggests complex animal life may have first flourished in the deep ocean.

A new hollow nanoreactor mimics living cells to make hydrogen peroxide more efficiently using visible light. Its light-trapping cavity and proton-shuttling shell could open new possibilities for cleaner chemical manufacturing and artificial photosynthesis.

Glyphosate was long thought to be safe for honeybees because they lack the enzyme the chemical targets in weeds. However, researchers found that exposed bees foraged 13 percent less after only three days and showed changes in brain chemicals linked to behavior. Across a whole hive, that decline could reduce honey production, weaken pollination, and threaten long-term survival.

A mathematician working at Anthropic says he used the AI model Claude Fable 5 to uncover a remarkably simple counterexample to the Jacobian conjecture, a famous problem that has resisted mathematicians for more than a century. The result shows that the conjecture is false in three dimensions and above, although the original two-dimensional version remains unsolved.

Historic wildfires scorched huge areas of Spain and France, with one Spanish blaze burning an area about the size of New York City and a French fire generating a rare, towering fire cloud. A dangerous combination of lush winter growth, severe heat, drought, and strong winds helped turn the landscape into explosive fuel.

August brings four major celestial events, including a solar eclipse and the peak of the Perseid meteor shower. Dark New Moon skies could make the Perseids especially impressive, while Venus will blaze in the west after sunset. A deep partial lunar eclipse closes the month, darkening most of the Moon.

A simple change in posture may subtly affect how people feel and make decisions. Participants who sat upright reported greater feelings of pride and took more successful risks in a virtual balloon game than those who hunched over. Most did not realize researchers had influenced their posture, helping rule out the possibility that they were merely responding to expectations. The results suggest workplace ergonomics could influence more than physical comfort.

A group of brain cells called orexin neurons appears to help us keep working when reaching a reward becomes increasingly difficult. Blocking their activity weakened motivation in rats, pointing to a possible new target for understanding why people sometimes struggle to sustain goal-directed behavior.

An exceptionally preserved snake fossil from Brazil reveals that early snakes were far more diverse than scientists once thought. Detailed brain reconstructions show that Tametara mirim was adapted for burrowing, while another ancient snake was suited to life above ground. Other fossils point to marine lifestyles as well. By 80 million years ago, snakes were already experimenting with very different habitats and sensory systems.

A long-term brain study found that common risks such as smoking, high blood pressure, heart disease, and high blood lipids were strongly linked to damage associated with vascular dementia. The findings suggest that healthier lifestyle choices could help delay dementia by reducing several harmful brain changes at once.

Scientists have successfully generated electricity with a hydrogen turbine that produces its own pressure through detonation waves instead of relying on a mechanical compressor. The breakthrough could unlock dramatically more efficient power systems for clean energy and future aviation.